Although the genome contains all the information necessary for maintenance and perpetuation of life, it is the proteome that repairs, duplicates and expresses the genome and actually performs most cellular functions.Here we reveal strong phenotypes of physiological oxidative proteome damage at the functional and genomic levels.Genome-wide mutations
The R Language: An Engine for Bioinformatics and Data Science
The R programming Preamplifiers language is approaching its 30th birthday, and in the last three decades it has achieved a prominent role in statistics, bioinformatics, and data science in general.It currently ranks among the top 10 most popular languages worldwide, and its community has produced tens of thousands of extensions and packages, with s
Role of EZH2-mediated H3K27me3 in placental ADAM12-S expression: implications for fetoplacental growth
Abstract Background Enhancer of Samsung RF56M9540SR Family Hub™ 91cm Frost Free American Fridge Freezer zeste homolog 2 (EZH2)-mediated histone 3 lysine 27 trimethylation (H3K27me3) is a transcription silencing mark, which is indispensable for cell lineage specification at the early blastocyst stage.This epigenetic repression is maintained in pla
Antimicrobial Peptides: Identification of two Beta-Defensins in a Teleost Fish, the European Sea Bass (Dicentrarchus labrax)
Beta-defensins consist in a group of cysteine-rich antimicrobial peptides (AMPs), widely found throughout vertebrate Preamplifiers species, including teleost fish, with antimicrobial and immunomodulatory activities.However, although the European sea bass (Dicentrarchus labrax) is one of the most commercially important farmed fish species in the Med
Digital Financial Literacy and Life Satisfaction: Evidence from South Korea
Digital financial literacy is an emerging concept that refers to the ability to effectively use digital tools, platforms, and services to manage personal finances.While previous Above Ground Product (Pumps) studies have explored the behavioral effects of digital financial literacy, less is known about its broader well-being implications for financi